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Venture Capital

Longwood Fund

Longwood Fund backs early-stage and high-growth companies, typically pre-profit, from Boston, MA. It states a focus on healthcare & life sciences.

Disclosed holdings57
Earliest stated investment
HeadquartersBoston, MA
Stated fund size$170 billion sustained market/exit value

Stated investment criteria

What Longwood Fund says it buys

Read from Longwood Fund’s own website in August 2026. This is what the firm says it buys, not what anyone has recorded it buying, and figures are shown in the currency the firm itself used - nothing here is converted. Every line links to the page it was read from.

People listed on its team page81

A stated mandate is a firm’s description of itself and was true of the page on the day it was read; firms widen and narrow what they will look at without updating the site. The team figure counts the people the firm shows on one team page, so it is a floor rather than a headcount: firms that split their team across tabs or load it in pages will read low. Nothing here is a commitment by Longwood Fund to consider any particular business, and nothing on this page is represented as being for sale.

Regulatory record

How Longwood Fund is registered

From this firm's Form ADV, the annual filing every registered and exempt investment adviser makes to the SEC.

Adviser statusExempt reporting adviser
Regulatory assets under managementNot reported by an ERA
Private funds advised12 · $456m gross
SEC adviser numberCRD 281220

An exempt reporting adviser is not required to report regulatory assets under management, so the blank above means the question was not asked rather than that the answer is unknown. Where a figure exists it is the gross asset value of the private funds the firm advises, which is a different and usually larger measure.

Portfolio

Disclosed holdings

Companies Longwood Fund lists on its own website. No investment years are published.

CompanyInvestedYears heldRecorded transaction
25+ portfolio companies in biotech
Aavantgarde
Aavantgardebio
Alnara
Archer
Avenzo
Bbot
Be Bio
Bebiopharma
Bicycletherapeutics
Bridgebio
Calithera Biosciences
Carbon
Channel Medsystems
Coultreon
Coultreon Biopharma
Crystalys
Dem
Dembiopharma
Engrail
Evommune
Grail
Illuminoss
Immunitas Therapeutics
Industry Events
Interius
Interiusbio
Kalvista
Kalvista Pharmaceuticals
Khartis
Khartis Therapeutics
Lassentherapeutics
Mediar
Millendo Therapeutics
Mitobridge
Neomorph
Newleos
Photys
Progentos
Ptc Therapeutics
Ptcbio
Pulmocide
Pyxisoncology
Rectify
Rectifypharma
Sidewinder
Sidewinderbio
Sitryx
Solu
Solutherapeutics
Tscan
Verastem
Weaver
Werewolf
Xaira
Xylocor
oncology

Compiled from Longwood Fund’s published portfolio page. Where a recorded transaction is shown, that company was the target of a reported deal and has most likely already been realised. Nothing here is represented as being for sale.

Valuation context

Transaction values in Healthcare & Life Sciences

What companies have actually sold for in healthcare & life sciences, across 1,263 recorded transactions.

Median consideration$110m
Middle 50%$30m-$318m
Revenue multiple2.8×
EBITDA multiple12.5×

The full healthcare & life sciences picture - most active acquirers, recent transactions and every investor in the sector.

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Comparable investors

Similar mandates

Other venture capital investors active in healthcare & life sciences.