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Venture Capital

Pappas Capital

Pappas Capital backs early-stage and high-growth companies, typically pre-profit, from United States. It states a focus on healthcare & life sciences.

Disclosed holdings91
Earliest stated investment
HeadquartersUnited States
Largest single fundNot stated

Stated investment criteria

What Pappas Capital says it buys

Read from Pappas Capital’s own website in August 2026. This is what the firm says it buys, not what anyone has recorded it buying, and figures are shown in the currency the firm itself used - nothing here is converted. Every line links to the page it was read from.

People listed on its team page211

A stated mandate is a firm’s description of itself and was true of the page on the day it was read; firms widen and narrow what they will look at without updating the site. The team figure counts the people the firm shows on one team page, so it is a floor rather than a headcount: firms that split their team across tabs or load it in pages will read low. Nothing here is a commitment by Pappas Capital to consider any particular business, and nothing on this page is represented as being for sale.

Regulatory record

How Pappas Capital is registered

From this firm's Form ADV, the annual filing every registered and exempt investment adviser makes to the SEC.

Adviser statusExempt reporting adviser
Regulatory assets under managementNot reported by an ERA
Private funds advised8 · $165m gross
SEC adviser numberCRD 163346

An exempt reporting adviser is not required to report regulatory assets under management, so the blank above means the question was not asked rather than that the answer is unknown. Where a figure exists it is the gross asset value of the private funds the firm advises, which is a different and usually larger measure.

Portfolio

Disclosed holdings

Companies Pappas Capital lists on its own website. No investment years are published.

CompanyInvestedYears heldRecorded transaction
2026 -- Minoryx Therapeutics and Neuraxpharm Group
4DMT
4d Molecular Therapeutics
Achillion
Achillion Pharmaceuticals
Aclara Biosciences
Aer Therapeutics
Afferent
Afferent Pharmaceuticals
Aktis Oncology
Allievex
Amplyx
Amplyx Pharmaceuticals
Anthera
Anthera Pharmaceuticals
Arena
Arena Pharmaceuticals
ArgoMed
Athersys
Balance Therapeutics
BaroSense
Bayhill Therapeutics
Bioatla
Biosyntech
Braincells
Calyx Therapeutics
Cardiodx
Cenerx Biopharma
Cequent Pharmaceuticals
Cerexa
Chimerix
Cognetix
Colucid Pharmaceuticals
Curasen Therapeutics
Curzion Pharmaceuticals
Cyclerion Therapeutics
Dynogen Pharmaceuticals
Ebm Solutions
Elitra Phramaceuticals
Emerald Bioagriculture
Enlaza Therapeutics
Envisia Therapeutics
Flowcardia
Gentis
Germany
Illuminoss Medical
Istari Oncology
July 24
Kezar Life Sciences
Lead Therapeutics
Liposcience
Liquidia Technologies
Lumena Pharmaceuticals
Marina Biotech
Methylgene
Milestone Pharmaceuticals
Mirum Pharmaceuticals
NVCA
Nereus
Nuvasive
Optherion
Orphomed
Panacos Pharmaceuticals
Peninsula Pharmaceuticals
Plexigen
Plexxikon
Reneo Pharmaceuticals Inc
Reprogenesis
Ribometrix
Rotation Medical
Selventa
Sensys Medical
Signase
Solu Therapeutics
Spain and DÜSSELDORF
Spherics
Syndax Pharmaceuticals
Syntonix Pharmaceuticals
Targegen
Tesaro
Thrasos Therapeutics
Tune Therapeutics
Tyrx
Ultragenyx Pharmaceutical
Variagenics
Velosbio
Veralox Therapeutics
Webtoffee
X Ceptor Therapeutics
bio
nc-biotech

Compiled from Pappas Capital’s published portfolio page. Where a recorded transaction is shown, that company was the target of a reported deal and has most likely already been realised. Nothing here is represented as being for sale.

Valuation context

Transaction values in Healthcare & Life Sciences

What companies have actually sold for in healthcare & life sciences, across 1,263 recorded transactions.

Median consideration$110m
Middle 50%$30m-$318m
Revenue multiple2.8×
EBITDA multiple12.5×

The full healthcare & life sciences picture - most active acquirers, recent transactions and every investor in the sector.

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Comparable investors

Similar mandates

Other venture capital investors active in healthcare & life sciences.